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CSNK2B Antibody (C-term F168)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CSNK2B Antibody (C-term F168) AP7075e
    Western blot analysis of lysate from HUVEC cell line, using CSNK2B Antibody(Cat. #AP7075e). AP7075e was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P67870
Other Accession P28021, P67874, P67873, P67872, P67871, Q91398, P67869, P67868
Reactivity Human
Predicted Bovine, Chicken, Zebrafish, Mouse, Pig, Rabbit, Rat, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 24942 Da
Antigen Region 153-184 aa
Additional Information
Gene ID 1460
Other Names Casein kinase II subunit beta, CK II beta, Phosvitin, Protein G5a, CSNK2B, CK2N, G5A
Target/Specificity This CSNK2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-184 amino acids from the C-terminal region of human CSNK2B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCSNK2B Antibody (C-term F168) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSNK2B (HGNC:2460)
Synonyms CK2N, G5A
Function Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:11239457, PubMed:16818610). Participates in Wnt signaling (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

CSNK2B is the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.

References

Schwartz, E.I., et al., Mol. Cell. Biol. 24(21):9580-9591 (2004).
Lee, G., et al., J. Biol. Chem. 279(8):6834-6839 (2004).
Lim, A.C., et al., J. Biol. Chem. 279(6):4433-4439 (2004).
Singh, D.K., et al., Virology 313(2):435-451 (2003).
Szebeni, A., et al., J. Biol. Chem. 278(11):9107-9115 (2003).

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$ 182.50
$ 70.00
Cat# AP7075e
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