|Application ||WB, E|
|Other Accession||P28021, P67874, P67873, P67872, P67871, Q91398, P67869, P67868|
|Predicted||Bovine, Chicken, Zebrafish, Mouse, Pig, Rabbit, Rat, Xenopus|
|Calculated MW||24942 Da|
|Antigen Region||153-184 aa|
|Other Names||Casein kinase II subunit beta, CK II beta, Phosvitin, Protein G5a, CSNK2B, CK2N, G5A|
|Target/Specificity||This CSNK2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-184 amino acids from the C-terminal region of human CSNK2B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CSNK2B Antibody (C-term F168) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.|
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Provided below are standard protocols that you may find useful for product applications.
CSNK2B is the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
Schwartz, E.I., et al., Mol. Cell. Biol. 24(21):9580-9591 (2004).
Lee, G., et al., J. Biol. Chem. 279(8):6834-6839 (2004).
Lim, A.C., et al., J. Biol. Chem. 279(6):4433-4439 (2004).
Singh, D.K., et al., Virology 313(2):435-451 (2003).
Szebeni, A., et al., J. Biol. Chem. 278(11):9107-9115 (2003).
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