|Application ||WB, IHC-P, E|
|Other Accession||Q8R2W9, Q08DA5|
|Calculated MW||41094 Da|
|Antigen Region||1-30 aa|
|Other Names||Pantothenate kinase 3, hPanK3, Pantothenic acid kinase 3, PANK3|
|Target/Specificity||This PANK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PANK3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PANK3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the physiological regulation of the intracellular CoA concentration.|
|Tissue Location||Highly expressed in the liver.|
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Provided below are standard protocols that you may find useful for product applications.
PANK3 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.
Zhou, B., et al., Nat. Genet. 28(4):345-349 (2001).
Robishaw, J.D., et al., Am. J. Physiol. 248 (1 PT 1), E1-E9 (1985) (): ().
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