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SEPSH2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEPSH2 Antibody (Center) AP7188b
    Western blot analysis of anti-SEPSH2 Pab(Cat. #AP7188b) in HepG2 cell line lysate (35ug/lane). SEPSH2(arrow) was detected using the purified Pab.
  • IHC-P - SEPSH2 Antibody (Center) AP7188b
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99611
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47305 Da
Antigen Region 171-201 aa
Additional Information
Gene ID 22928
Other Names Selenide, water dikinase 2, Selenium donor protein 2, Selenophosphate synthase 2, SEPHS2, SPS2
Target/Specificity This SEPSH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-201 amino acids from the Central region of human SEPSH2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEPSH2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SPS2
Function Synthesizes selenophosphate from selenide and ATP.
Research Areas
Citations (0)

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This protein encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop.


Tamura, T., et al., Proc. Natl. Acad. Sci. U.S.A. 101(46):16162-16167 (2004).
Lescure, A., et al., J. Biol. Chem. 274(53):38147-38154 (1999).
Guimaraes, M.J., et al., Proc. Natl. Acad. Sci. U.S.A. 93(26):15086-15091 (1996).
Guimaraes, M.J., et al., Development 121(10):3335-3346 (1995).

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$ 295.00
$ 99.00
Cat# AP7188b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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