STK19 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P49842 |
Other Accession | Q5ST75 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 28465 Da |
Antigen Region | 278-308 aa |
Gene ID | 8859 |
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Other Names | Serine/threonine-protein kinase 19, Protein G11, Protein RP1, STK19, G11, RP1 |
Target/Specificity | This STK19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-308 amino acids from the C-terminal region of human STK19. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | STK19 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STK19 {ECO:0000303|PubMed:30712867, ECO:0000312|HGNC:HGNC:11398} |
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Function | [Isoform 1]: Inactive serine/threonine-protein kinase (PubMed:32531246, PubMed:32531245) (Probable). May control NRAS activity via an associated kinase (PubMed:32531246) (Probable). |
Cellular Location | [Isoform 3]: Nucleus. Note=Very tightly chromatin-associated |
Tissue Location | Monocytes, hepatocytes, epithelial cells, T- and B- lymphocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SSTK19 is a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation.
References
Gomez-Escobar, N., et al., J. Biol. Chem. 273(47):30954-30960 (1998).
Yang, Z., et al., Genomics 53(3):338-347 (1998).
Ulgiati, D., et al., Immunogenetics 43(4):250-252 (1996).
Sargent, C.A., et al., Hum. Mol. Genet. 3(3):481-488 (1994).
Shen, L., et al., J. Biol. Chem. 269(11):8466-8476 (1994).
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