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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CDKL5 (STK9) Antibody (C-term)   

CDKL5 (STK9) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CDKL5 (STK9) Antibody (C-term) AP7244b
    Anti-STK9 Antibody (F997) at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 116 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - CDKL5 (STK9) Antibody (C-term) AP7244b
    The anti-STK9 Pab (Cat. #AP7244b) is used in Western blot to detect STK9 in mouse lung tissue lysate.
  • IHC-P - CDKL5 (STK9) Antibody (C-term) AP7244b
    Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with STK9 Antibody (C-term)(Cat.#AP7244b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O76039
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 115538 Da
Antigen Region 982-1012 aa
Additional Information
Gene ID 6792
Other Names Cyclin-dependent kinase-like 5, Serine/threonine-protein kinase 9, CDKL5, STK9
Target/Specificity This CDKL5 (STK9) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 982-1012 amino acids from the C-terminal region of human CDKL5 (STK9).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDKL5 (STK9) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDKL5
Synonyms STK9
Function Mediates phosphorylation of MECP2.
Cellular Location Nucleus.
Tissue Location Expressed in brain, lung, kidney, prostate, ovary, placenta, pancreas and testis
Research Areas
Citations (0)

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Defects in STK9, a dual-specificity serine/threonine kinase, are a cause of atypical Rett syndrome. Rett syndrome is an X-linked dominant disease. It is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood. Rett syndrome due to CDKL5-associated mutations is characterized by a severe early-onset phenotype and atypical features such as infantile spasms.


Kalscheuer, V.M., et al., Am. J. Hum. Genet. 72(6):1401-1411 (2003).
Montini, E., et al., Genomics 51(3):427-433 (1998).

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$ 295.00
$ 99.00
Cat# AP7244b
(40 western blots)
Availability: In Stock
Bulk Size
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