SNRK Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q9NRH2 |
Other Accession | Q63553, Q8VDU5 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 84276 Da |
Antigen Region | 320-349 aa |
Gene ID | 54861 |
---|---|
Other Names | SNF-related serine/threonine-protein kinase, SNF1-related kinase, SNRK {ECO:0000312|EMBL:AAH715671} |
Target/Specificity | This SNRK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-349 amino acids from the Central region of human SNRK. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SNRK Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SNRK {ECO:0000312|EMBL:AAH71567.1} |
---|---|
Function | May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis |
Provided below are standard protocols that you may find useful for product applications.
Background
SNRK, as known as,SNF-related serine/threonine-protein kinase, may play a role in hematopoietic cell proliferation or differentiation and a potential mediator of neuronal apoptosis.It is activated by phosphorylation on Thr-173 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.
References
Becker, W., et al., Eur. J. Biochem. 235(3):736-743 (1996).
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