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SNRK Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SNRK Antibody (Center) AP7249c
    Western blot analysis of SNRK (arrow) using rabbit polyclonal SNRK Antibody (Center) (Cat. #AP7249c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNRK gene.
    detail
  • IHC-P - SNRK Antibody (Center) AP7249c
    SNRK Antibody (Center) (Cat. #AP7249c)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SNRK Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
  • CITATIONS: 1
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q9NRH2
Other Accession Q63553, Q8VDU5
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 84276 Da
Antigen Region 320-349 aa
Additional Information
Gene ID 54861
Other Names SNF-related serine/threonine-protein kinase, SNF1-related kinase, SNRK {ECO:0000312|EMBL:AAH715671}
Target/Specificity This SNRK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-349 amino acids from the Central region of human SNRK.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNRK Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNRK {ECO:0000312|EMBL:AAH71567.1}
Function May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.
Cellular Location Nucleus.
Tissue Location Expressed in hematopoietic progenitor cells and leukemic cell lines. Weakly expressed in the testis
Research Areas
Citations ( 0 )

Background

SNRK, as known as,SNF-related serine/threonine-protein kinase, may play a role in hematopoietic cell proliferation or differentiation and a potential mediator of neuronal apoptosis.It is activated by phosphorylation on Thr-173 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.

References

Becker, W., et al., Eur. J. Biochem. 235(3):736-743 (1996).

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$ 182.50
$ 70.00
Cat# AP7249c
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