|Application ||WB, IHC-P, E|
|Other Accession||Q62443, P47971|
|Calculated MW||47122 Da|
|Antigen Region||364-393 aa|
|Other Names||Neuronal pentraxin-1, NP1, 47 kDa taipoxin-binding protein, Neuronal pentraxin I, NP-I, Nptx1|
|Target/Specificity||This NP1(Nptx1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human NP1(Nptx1).|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NP1(Nptx1) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
NPTX1 is a member of the neuronal pentraxin gene family. Human neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin.
Hossain,M.A., J. Neurosci. 24 (17), 4187-4196 (2004)
Schlimgen,A.K., Neuron 14 (3), 519-526 (1995)
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