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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CCNA2 Antibody (C-term)   

CCNA2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CCNA2 Antibody (C-term) AP7292b
    Western blot analysis of CCNA2 (arrow) using rabbit polyclonal CCNA2 Antibody (C-term) (Cat.#AP7292b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CCNA2 gene (Lane 2) (Origene Technologies).
  • IHC-P - CCNA2 Antibody (C-term) AP7292b
    Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CCNA2 antibody (C-term) (Cat.#AP7292b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20248
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48551 Da
Antigen Region 358-389 aa
Additional Information
Gene ID 890
Other Names Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA
Target/Specificity This CCNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human CCNA2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCNA2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCNA2
Synonyms CCN1, CCNA
Function Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
Cellular Location Nucleus. Cytoplasm. Note=Cytoplasmic when associated with SCAPER
Research Areas
Citations (0)

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CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.


Henglein B.,Proc. Natl. Acad. Sci. U.S.A. 91:5490-5494(1994)
Wang J.,Nature 343:555-557(1990)
Tsang,W.Y.,J. Cell Biol. 178 (4), 621-633 (2007)

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Cat# AP7292b
(40 western blots)
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