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Aromatase (CYP19A1) Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Aromatase (CYP19A1) Antibody (Center) AP7293c
    Western blot analysis of anti-CYP19A1(Center) Pab (Cat.#AP7293c) in HL60 cell line lysates (35ug/lane). CYP19A1(arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11511
Other Accession Q29605
Reactivity Human
Predicted Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57883 Da
Antigen Region 221-253 aa
Additional Information
Gene ID 1588
Other Names Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19
Target/Specificity This Aromatase (CYP19A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-253 amino acids from the Central region of human Aromatase (CYP19A1).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAromatase (CYP19A1) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP19A1
Synonyms ARO1, CYAR, CYP19
Function Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
Cellular Location Membrane; Peripheral membrane protein.
Tissue Location Brain, placenta and gonads.
Research Areas
Citations (0)

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CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.


Ikeda,S.,Am. J. Gastroenterol. 103 (6), 1476-1487 (2008)
Dos Santos,(er) DNA Cell Biol. (2008) In press
Nelson,Pharmacogenetics 14 (1), 1-18 (2004)

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$ 295.00
$ 99.00
Cat# AP7293c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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