- CITATIONS: 1
|Application ||WB, IHC-P, E|
|Calculated MW||56166 Da|
|Antigen Region||89-119 aa|
|Other Names||Cytosol aminopeptidase, Leucine aminopeptidase 3, LAP-3, Leucyl aminopeptidase, Peptidase S, Proline aminopeptidase, Prolyl aminopeptidase, LAP3, LAPEP, PEPS|
|Target/Specificity||This LAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-119 amino acids from the N-terminal region of human LAP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LAP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.|
Provided below are standard protocols that you may find useful for product applications.
LAP3 is presumably involved in the processing and regular turnover of intracellular proteins. It catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro.
Goto,Y.,FEBS Lett. 580 (7), 1833-1838 (2006)
Matsushima,M.,Biochem. Biophys. Res. Commun. 178 (3), 1459-1464 (1991)
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