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PITX1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | P78337 |
| Other Accession | P52906, O18400, Q9I8K3, Q6QU75, Q9PWR3, Q9R0W1, P97474, Q99697, Q9W5Z2, O93385, Q9W751, Q99NA7, P70314, P56673 |
| Reactivity | Human |
| Predicted | Chicken, Mouse, Rat, Xenopus, Zebrafish, Drosophila, C.Elegans |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 34128 Da |
| Antigen Region | 123-150 aa |
| Gene ID | 5307 |
|---|---|
| Other Names | Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1, PITX1, BFT, PTX1 |
| Target/Specificity | This PITX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-150 amino acids from the Central region of human PITX1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PITX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PITX1 |
|---|---|
| Synonyms | BFT, PTX1 |
| Function | Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PITX1 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
References
Grimminger,P., Ling,F.C. Anticancer Res. 29 (4), 1281-1286 (2009)
Gurnett,C.A., Alaee,F. Am. J. Hum. Genet. 83 (5), 616-622 (2008)
Philippi,A., Tores,F. BMC Med. Genet. 8, 74 (2007)
Shang,J., Li,X. Genomics 40 (1), 108-113 (1997)
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