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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CPN1 Antibody (N-term)   

CPN1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CPN1 Antibody (N-term) AP7337a
    All lanes : Anti-CPN1 Antibody (N-term) at 1:1000 dilution Lane 1: human liver lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - CPN1 Antibody (N-term) AP7337a
    Western blot analysis of CPN1 antibody (N-term) (Cat.#AP7337a) in K562, CEM, HEpG2 cell line lysates and mouse liver tissue lysates (35ug/lane). CPN1(arrow) was detected using the purified Pab.
  • WB - CPN1 Antibody (N-term) AP7337a
    Western blot analysis of CPN1 (arrow) using rabbit polyclonal CPN1 Antibody (N-term) (Cat. #AP7337a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CPN1 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15169
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 52286 Da
Antigen Region 52-81 aa
Additional Information
Gene ID 1369
Other Names Carboxypeptidase N catalytic chain, CPN, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, Serum carboxypeptidase N, SCPN, CPN1, ACBP
Target/Specificity This CPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human CPN1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCPN1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPN1
Synonyms ACBP
Function Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Cellular Location Secreted, extracellular space.
Tissue Location Synthesized in the liver and secreted in plasma
Research Areas
Citations (0)

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CPN1 is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The protein is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This protein is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits.


Davis,D.A., Singer,K.E. Blood 105 (12), 4561-4568 (2005)
Riley,D.A., Tan,F. Genomics 50 (1), 105-108 (1998)
Hendriks,D., Vingron,M. Biol. Chem. Hoppe-Seyler 374 (9), 843-849 (1993)

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$ 295.00
$ 99.00
Cat# AP7337a
(40 western blots)
Availability: In Stock
Bulk Size
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