|Application ||WB, E|
|Calculated MW||50792 Da|
|Antigen Region||127-156 aa|
|Other Names||Krueppel-like factor 5, Basic transcription element-binding protein 2, BTE-binding protein 2, Colon krueppel-like factor, GC-box-binding protein 2, Intestinal-enriched krueppel-like factor, Transcription factor BTEB2, KLF5, BTEB2, CKLF, IKLF|
|Target/Specificity||This KLF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the Central region of human KLF5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLF5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BTEB2, CKLF, IKLF|
|Function||Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes.|
|Tissue Location||Expressed only in testis and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
KLF5 is a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, the protein is thought to be a transcription factor.
Guo,P., Dong,X.Y. J. Biol. Chem. 284 (10), 6071-6078 (2009)
Lee,M.Y., Moon,J.S. Biochem. J. 417 (1), 313-322 (2009)
Du,J.X., Bialkowska,A.B. J. Biol. Chem. 283 (46), 31991-32002 (2008)
Miyamoto,S., Suzuki,T. Mol. Cell. Biol. 23 (23), 8528-8541 (2003)
Shi,H., Zhang,Z. Nucleic Acids Res. 27 (24), 4807-4815 (1999)
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