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MYO1A Antibody (Center S291)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MYO1A Antibody (Center S291) AP7343c
    Western blot analysis of MYO1A antibody (Center S291) (Cat.#AP7343c) in Jurkat cell line lysates (35ug/lane). MYO1A (arrow) was detected using the purified Pab.
  • FC - MYO1A Antibody (Center S291) AP7343c
    MYO1A Antibody (Center S291) (Cat. #AP7343c) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBC5
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 118401 Da
Antigen Region 276-304 aa
Additional Information
Gene ID 4640
Other Names Unconventional myosin-Ia, Brush border myosin I, BBM-I, BBMI, Myosin I heavy chain, MIHC, MYO1A, MYHL
Target/Specificity This MYO1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human MYO1A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMYO1A Antibody (Center S291) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYO1A
Synonyms MYHL
Function Involved in directing the movement of organelles along actin filaments.
Research Areas
Citations (0)

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MYO1A belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein envelops an actin core bundle that, by comparison, is static in structure.


D'Adamo,P., Pinna,M. Hum. Genet. 112 (3), 319-320 (2003)
Hoshimaru,M., Fujio,Y. J. Biochem. 106 (3), 455-459 (1989)
Durrbach,A., Collins,K. Proc. Natl. Acad. Sci. U.S.A. 93 (14), 7053-7058 (1996)

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$ 295.00
$ 99.00
Cat# AP7343c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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