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SERPINH1 Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP7366b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
  • Specification
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  • Backgrounds

SERPINH1 Antibody (C-term) - Product info

ApplicationWB, IHC, FC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionP50454
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW46441 Da

SERPINH1 Antibody (C-term) - Additional info

Gene ID 871
Other Names
SERPINH1; CBP1; CBP2; HSP47; SERPINH2; Serpin H1; 47 kDa heat shock protein; Arsenic-transactivated protein 3; Cell proliferation-inducing gene 14 protein; Collagen-binding protein; Rheumatoid arthritis-related antigen RA-A47
Target/Specificity
This SERPINH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389~418 amino acids from the C-terminal region of human SERPINH1.
Dilution
WB~~1:50~100
IHC~~1:50~100
FC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
SERPINH1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

SERPINH1 Antibody (C-term) - Protein Information

Name SERPINH1
Synonyms CBP1, CBP2, HSP47, SERPINH2
Function
Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen
Cellular Location
Endoplasmic reticulum lumen.

SERPINH1 Antibody (C-term) - Related products

AP7366b: SERPINH1 Antibody (C-term)

AP7366c: SERPINH1 Antibody (Center)

RI14789: SERPINH1 predesign siRNA

DC03909: Human SERPINH1 cDNA Clone

LY11189a: SERPINH1 Over-expression Lysate

BP7366b: SERPINH1 Antibody (C-term) Blocking Peptide

BP7366c: SERPINH1 Antibody (Center) Blocking Peptide

AT3827a: SERPINH1 Antibody (monoclonal) (M01)

SERPINH1 Antibody (C-term) - Application data

  • Western blot analysis of SERPINH1 antibody (C-term) (Cat.# AP7366b) in Hela cell line lysates (35ug/lane). SERPINH1 (arrow) was detected using the purified Pab.

  • SERPINH1 Antibody (C-term) (RB18953) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SERPINH1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

  • SERPINH1 Antibody (C-term) (Cat. #AP7366b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

SERPINH1 Antibody (C-term) - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

SERPINH1 is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis.

REFERENCES

Araki,K., Br. J. Cancer 101 (3), 492-497 (2009) Katagata,Y., J. Dermatol. Sci. 49 (1), 33-38 (2008)