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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CSNK1A1 Antibody (C-term)   

CSNK1A1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - CSNK1A1 Antibody (C-term) AP7400a
    Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CK1a antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • WB - CSNK1A1 Antibody (C-term) AP7400a
    Western blot analysis of anti-CK1a Pab (Cat. #AP7400a) in A375 cell lysate. CK1a (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48729
Other Accession P67963, P67962
Reactivity Human
Predicted Chicken, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38915 Da
Antigen Region 309-337 aa
Additional Information
Gene ID 1452
Other Names Casein kinase I isoform alpha, CKI-alpha, CK1, CSNK1A1
Target/Specificity This CSNK1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human CSNK1A1.
Dilution IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCSNK1A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSNK1A1
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Note=Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis
Research Areas
Citations ( 0 )


Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.


Liu, C., et al., Cell 108(6):837-847 (2002).
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Fish, K.J., et al., J. Biol. Chem. 270(25):14875-14883 (1995).
Tapia, C., et al., FEBS Lett. 349(2):307-312 (1994).

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$ 295.00
$ 99.00
Cat# AP7400a
(40 western blots)
Availability: In Stock
Bulk Size
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