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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CAMK2A Antibody (C-term E370)   

CAMK2A Antibody (C-term E370)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CAMK2A Antibody (C-term E370) AP7418b
    Western blot analysis of anti-CAMK2A Antibody (C-term E370) (Cat.#AP7418b) in 293 cell line lysates (35ug/lane). CAMK2A(arrow) was detected using the purified Pab.
  • WB - CAMK2A Antibody (C-term E370) AP7418b
    Western blot analysis of CAMK2A (arrow) using rabbit polyclonal CAMK2A Antibody (C-term E370) (Cat.#AP7418b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMK2A gene (Lane 2).
  • IHC-P - CAMK2A Antibody (C-term E370) AP7418b
    Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2A (C-term E370) (Cat.#AP7418b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UQM7
Other Accession P11275, P11798
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54088 Da
Antigen Region 344-371 aa
Additional Information
Gene ID 815
Other Names Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968
Target/Specificity This CAMK2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-371 amino acids from the C-terminal region of human CAMK2A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCAMK2A Antibody (C-term E370) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CAMKA, KIAA0968
Function CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
Cellular Location Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse Note=Postsynaptic lipid rafts.
Research Areas
Citations (0)

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CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by the gene for CAMK2A is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.


Lee,C.W., Mol. Pharmacol. 73 (5), 1454-1464 (2008)
Yuan,K., Lab. Invest. 87 (9), 938-950 (2007)

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$ 295.00
$ 99.00
Cat# AP7418b
(40 western blots)
Availability: In Stock
Bulk Size
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