|Application ||WB, E|
|Calculated MW||37859 Da|
|Antigen Region||193-224 aa|
|Other Names||Homeobox protein HMX3, Homeobox protein H6 family member 3, Homeobox protein Nkx-51, Hmx3, Nkx-51, Nkx5-1|
|Target/Specificity||This Mouse Hmx3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-224 amino acids from the C-terminal region of mouse Hmx3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Hmx3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS.|
|Tissue Location||Expressed in the developing CNS, including a specific expression in vestibular structures throughout inner ear development.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Hmx3 is a transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. This protein binds to the 5'-CAAGTG-3' core sequence. It controls semicircular canal formation in the inner ear and is also required for hypothalamic/pituitary axis of the CNS.
Mennerich D., Hoffmann S.,Biol. Chem. 380:1041-1048(1999)
Rinkwitz-Brandt S., Justus M.,Mech. Dev. 52:371-381(1995)
Rinkwitz-Brandt S., Arnold H.H., Bober E.Hear. Res. 99:129-138(1996)
Amendt B.A., Sutherland L.B.,J. Biol. Chem. 274:11635-11642(1999)
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