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ABCC4 Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP7436b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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ABCC4 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | O15439 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 149527 Da |
ABCC4 Antibody (C-term) - Additional info | |
| Gene ID 10257 | |
| Other Names ABCC4; MRP4; Multidrug resistance-associated protein 4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B | |
| Target/Specificity This ABCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1124~1153 amino acids from the C-terminal region of human ABCC4. | |
| Dilution WB~~1:50~100WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABCC4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABCC4 Antibody (C-term) - Protein Information | |
| Name ABCC4 | |
| Synonyms MRP4 | |
| Function May be an organic anion pump relevant to cellular detoxification | |
| Cellular Location Membrane; Multi-pass membrane protein. | |
| Tissue Location Widely expressed, with particularly high levels in prostate, but is barely detectable in liver | |
ABCC4 Antibody (C-term) - Related products
AP7436b: ABCC4 Antibody (C-term)
RI10022: ABCC4 predesign siRNA
BP7436b: ABCC4 Antibody (C-term) Blocking Peptide
ABCC4 Antibody (C-term) - Application data
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Western blot analysis of anti-ABCC4 Antibody (C-term)(Cat.#AP7436b) in CEM cell line lysates (35ug/lane). ABCC4 (arrow) was detected using the purified Pab.
ABCC4 Antibody (C-term) - Research Areas
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BACKGROUND
ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.
REFERENCES
Lee K., Belinsky M.G., Bell D.W.Cancer Res. 58:2741-2747(1998) Adachi M., Sampath J., Lan L.B.J. Biol. Chem. 277:38998-39004(2002) Kool M., de Haas M., Scheffer G.L.Cancer Res. 57:3537-3547(1997) Janke D., Mehralivand S., Strand D.Hum. Mutat. 29:659-669(2008)
