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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DCXR Antibody (Center)   

DCXR Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DCXR Antibody (Center) AP7443c
    Western blot analysis of anti-DCXR Antibody (Center)(Cat.#AP7443c) in mouse lung tissue lysates (35ug/lane). DCXR (arrow) was detected using the purified Pab.
  • IHC-P - DCXR Antibody (Center) AP7443c
    Formalin-fixed and paraffin-embedded human kidney carcinoma with DCXR Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - DCXR Antibody (Center) AP7443c
    Flow cytometric analysis of NCI-H292 cells using DCXR Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z4W1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25913 Da
Antigen Region 79-106 aa
Additional Information
Gene ID 51181
Other Names L-xylulose reductase, XR, Carbonyl reductase II, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, kiDCR, Sperm surface protein P34H, DCXR
Target/Specificity This DCXR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-106 amino acids from the Central region of human DCXR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDCXR Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SDR20C1
Function Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L- xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Cellular Location Membrane; Peripheral membrane protein. Note=Probably recruited to membranes via an interaction with phosphatidylinositol.
Tissue Location Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis
Research Areas
Citations (0)

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DCXR is an enzyme that has both diacetyl reductase and L-xylulose reductase activities.


Nakagawa J., Ishikura S.J. Biol. Chem. 277:17883-17891(2002)
Xia X.Y., Xu X.F., Gao Y.Zhonghua Nan Ke Xue 9:24-27(2003)
El-Kabbani O., Chung R.P.-T.Acta Crystallogr. D 58:1379-1380(2002)

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Cat# AP7443c
(40 western blots)
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