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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CYP2J2 Antibody (N-term)   

CYP2J2 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CYP2J2 Antibody (N-term) AP7450a
    Western blot analysis of CYP2J2 Antibody (N-term) (Cat. #AP7450a) in HepG2 cell line lysates (35ug/lane). CYP2J2 (arrow) was detected using the purified Pab.
  • IHC-P - CYP2J2 Antibody (N-term) AP7450a
    Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP2J2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - CYP2J2 Antibody (N-term) AP7450a
    Flow cytometric analysis of HepG2 cells using CYP2J2 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51589
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57611 Da
Antigen Region 96-124 aa
Additional Information
Gene ID 1573
Other Names Cytochrome P450 2J2, Arachidonic acid epoxygenase, CYPIIJ2, CYP2J2
Target/Specificity This CYP2J2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the N-terminal region of human CYP2J2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCYP2J2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP2J2
Function This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Tissue Location Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney
Research Areas
Citations (0)

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CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.


Wu S., Moomaw C.R., Tomer K.B.J. Biol. Chem. 271:3460-3468(1996)
King L.M., Ma J., Srettabunjong S.Mol. Pharmacol. 61:840-852(2002)

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$ 295.00
$ 99.00
Cat# AP7450a
(40 western blots)
Availability: In Stock
Bulk Size
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