|Application ||WB, IF, E|
|Other Accession||P09066, Q05917, P52730, P52729, P09015|
|Predicted||Zebrafish, Xenopus, Chicken|
|Calculated MW||34211 Da|
|Antigen Region||243-271 aa|
|Other Names||Homeobox protein engrailed-2, Homeobox protein en-2, Hu-En-2, EN2|
|Target/Specificity||This EN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human EN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
EN2 is thought to have a role in controlling development. In Drosophila, the protein plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. This protein has been implicated in the control of pattern formation during development of the central nervous system.
Poole S.J., Law M.L.Genomics 4:225-231(1989)
Benayed R., Gharani N.Am. J. Hum. Genet. 77:851-868(2005)
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