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ARSB Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ARSB Antibody (Center) AP7460c
    Western blot analysis of ARSB Antibody (Center) (Cat. #AP7460c) in HL-60 cell line lysates (35ug/lane).ARSB (arrow) was detected using the purified Pab.
  • WB - ARSB Antibody (Center) AP7460c
    Western blot analysis of ARSB (arrow) using rabbit polyclonal ARSB Antibody (Center) (Cat. #AP7460c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ARSB gene (Lane 2) (Origene Technologies).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15848
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 59687 Da
Antigen Region 235-266 aa
Additional Information
Gene ID 411
Other Names Arylsulfatase B, ASB, N-acetylgalactosamine-4-sulfatase, G4S, ARSB
Target/Specificity This ARSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-266 amino acids from the Central region of human ARSB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsARSB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity).
Cellular Location Lysosome. Cell surface {ECO:0000250|UniProtKB:P50429}
Research Areas
Citations (0)

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ARSB belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B.


Peters C., Schmidt B.J. Biol. Chem. 265:3374-3381(1990)
Modaressi S., Rupp K.Biol. Chem. Hoppe-Seyler 374:327-335(1993)
Kobayashi T., Honke K.Biochim. Biophys. Acta 1159:243-247(1992)

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Cat# AP7460c
(40 western blots)
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