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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   VTN Antibody (C-term)   

VTN Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - VTN Antibody (C-term) AP7462B
    Western blot analysis of VTN Antibody (C-term) (Cat.#AP7462b) in NCI-H460(lane 1), HepG2(lane 2) cell line lysates (35ug/lane). VTN (arrow) was detected using the purified Pab.
  • IHC-P - VTN Antibody (C-term) AP7462B
    Formalin-fixed and paraffin-embedded human hepatocarcinoma with VTN Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - VTN Antibody (C-term) AP7462B
    Flow cytometric analysis of NCI-H292 cells using VTN Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04004
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54306 Da
Antigen Region 352-379 aa
Additional Information
Gene ID 7448
Other Names Vitronectin, VN, S-protein, Serum-spreading factor, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B, VTN
Target/Specificity This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-379 amino acids from the C-terminal region of human VTN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsVTN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VTN
Function Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Cellular Location Secreted, extracellular space.
Tissue Location Plasma.
Research Areas
Citations (0)

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VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.


Jenne D.E., Stanley K.K.EMBO J. 4:3153-3157(1985)
Sigurdardottir O., Wiman B.Biochim. Acta 1208:104-110(1994)
Seiffert D., Loskutoff D.J.J. Biol. Chem. 266:2824-2830(1991)

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Cat# AP7462B
(40 western blots)
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