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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GDF6 Antibody (C-term)   

GDF6 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GDF6 Antibody (C-term) AP7483B
    Western blot analysis of GDF6 antibody (C-term) (Cat.#AP7483b) in mouse kidney tissue lysates (35ug/lane). GDF6 (arrow) was detected using the purified Pab.
  • IHC-P - GDF6 Antibody (C-term) AP7483B
    Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - GDF6 Antibody (C-term) AP7483B
    Flow cytometric analysis of 293 cells using GDF6 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6KF10
Other Accession Q6HA10, P43028, P55106
Reactivity Human, Mouse
Predicted Bovine, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50662 Da
Antigen Region 326-353 aa
Additional Information
Gene ID 392255
Other Names Growth/differentiation factor 6, GDF-6, Bone morphogenetic protein 13, BMP-13, Growth/differentiation factor 16, GDF6, BMP13, GDF16
Target/Specificity This GDF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-353 amino acids from the C-terminal region of human GDF6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGDF6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GDF6
Synonyms BMP13, GDF16
Function Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development. May signal through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A.
Cellular Location Secreted.
Research Areas
Citations (0)

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GDF6 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this protein result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.


Tassabehji M., Fang Z.M.Hum. Mutat. 29:1017-1027(2008)

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Cat# AP7483B
(40 western blots)
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