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GHRHR Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GHRHR Antibody (C-term) AP7494b
    Western blot analysis of GHRHR antibody (C-term) (Cat.#AP7494b) in K562 cell line lysates (35ug/lane). GHRHR (arrow) was detected using the purified Pab.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q02643
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 47402 Da
Antigen Region 367-397 aa
Additional Information
Gene ID 2692
Other Names Growth hormone-releasing hormone receptor, GHRH receptor, Growth hormone-releasing factor receptor, GRF receptor, GRFR, GHRHR
Target/Specificity This GHRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-397 amino acids from the C-terminal region of human GHRHR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGHRHR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GHRHR
Function Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Pituitary gland.
Research Areas
Citations (0)
citation

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Background

GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in GHRHR gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.

References

Johansson,A., Jonasson,I. PLoS ONE 4 (2), E4464 (2009)
Squire,J., Zhou,A. Genomics 19 (1), 174-175 (1994)

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$ 182.50
$ 70.00
Cat# AP7494b
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