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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CDK10 Antibody (N-term)   

CDK10 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CDK10 Antibody (N-term) AP7516A
    Western blot analysis of CDK10 antibody (N-term) (Cat. #AP7516a) pre-incubated with (Lane1) and without (Lane 2) blocking peptide (Cat. #BP7516a) in A375 cell line lysate. CDK10 (arrow) was detected using the purified Pab.
  • IHC-P - CDK10 Antibody (N-term) AP7516A
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15131
Other Accession Q3UMM4
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41038 Da
Antigen Region 1-32 aa
Additional Information
Gene ID 8558
Other Names Cyclin-dependent kinase 10, Cell division protein kinase 10, Serine/threonine-protein kinase PISSLRE, CDK10
Target/Specificity This CDK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human CDK10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDK10 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDK10
Function Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells).
Research Areas
Citations ( 0 )


CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase.


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Brambilla, R., et al., Oncogene 9(10):3037-3041 (1994).
Grana, X., et al., Oncogene 9(7):2097-2103 (1994).
Morgan, D. O. Annu. Rev. Cell Dev. Biol. 13, 261 (1997)
Sherr, C. Science 274:1672 (1996)
Kamb A. TIG 11:136 (1995)
Zhang, H. et al, Cell 82, 915 (1995)
Parge, HE. et al., Science 262, 387 (1993)
Hershko, A. et al., Ann. Rev. Biochem. 61, 761 (1992)
Peters, JM. Curr. Biol. 10, 759 (1998)
Skowyra, D. etal., Cell 91, 209 (1997)
Ganoth D. et al., Nature Cell Biol. 3, 321-324 (2001)

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$ 295.00
$ 99.00
Cat# AP7516A
(40 western blots)
Availability: In Stock
Bulk Size
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