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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Thrombopoietin (TPO) Antibody (C-term)   

Thrombopoietin (TPO) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Thrombopoietin (TPO) Antibody (C-term) AP7557b
    Western blot analysis of anti-THPO(C-term) Pab (Cat.#AP7557b) in K562 cell line lysates (35ug/lane). THPO(arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40225
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37823 Da
Antigen Region 300-329 aa
Additional Information
Gene ID 7066
Other Names Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand, THPO, MGDF
Target/Specificity This Thrombopoietin (TPO) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-329 amino acids from the C-terminal region of human Thrombopoietin (TPO).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsThrombopoietin (TPO) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MGDF
Function Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Cellular Location Secreted.
Research Areas
Citations (0)

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Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. It is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.


Baker,J.E.,Cardiovasc. Res. 77 (1), 44-53 (2008)
Steinberg,O.,J. Pediatr. Hematol. Oncol. 29 (12), 822-825 (2007)
Kanayasu-Toyoda,T.,J. Biol. Chem. 282 (46), 33507-33514 (2007)

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$ 295.00
$ 99.00
Cat# AP7557b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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