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Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term)Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # Size Availability Price  
AP7559b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
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Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term) - Product info

ApplicationWB, IHC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionQ5JTZ9
Other AccessionA2RRN5
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW107340 Da

Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term) - Additional info

Gene ID 57505
Other Names
AARS2; AARSL; KIAA1270; Alanine--tRNA ligase, mitochondrial; Alanyl-tRNA synthetase
Target/Specificity
This AARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 841~871 amino acids from the C-terminal region of human AARS2.
Dilution
WB~~1:50~100
IHC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term) - Protein Information

Name AARS2
Synonyms AARSL, KIAA1270
Function
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity)
Cellular Location
Mitochondrion.

Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term) - Related products

AP7559b: Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term)

AP7559c: AARS2 Antibody (Center)

RI10005: AARS2 predesign siRNA

BP7559b: AARS2 Antibody (C-term) Blocking Peptide

Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term) - Application data

  • Western blot analysis of anti-AARS2 Pab (Cat.#AP7559b) in SK-BR-3 cell line lysates (35ug/lane).AARS2 (arrow) was detected using the purified Pab (1:60 dilution).

  • Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with AARS2 antibody (C-term) (Cat.#AP7559b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term) - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

Alanyl-tRNA synthetase 2 (AARS2) is an enzyme that catalyzes the chemical reaction: ATP + L-alanine + tRNAAla <---> AMP + diphosphate + L-alanyl-tRNAAla. This enzyme participates in alanine and aspartate metabolism and aminoacyl-tRNA biosynthesis.

REFERENCES

Bonnefond,L.,Biochemistry 44 (12), 4805-4816 (2005) Nakayama,M., Genome Res. 12 (11), 1773-1784 (2002)