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ACO2 Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP7561b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
ACO2 Antibody (C-term) - Product info | |
| Application | IHC, WB
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| Primary Accession | Q99798 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 85425 Da |
ACO2 Antibody (C-term) - Additional info | |
| Gene ID 50 | |
| Other Names ACO2; Aconitate hydratase, mitochondrial; Citrate hydro-lyase | |
| Target/Specificity This ACO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 633~662 amino acids from the C-terminal region of human ACO2. | |
| Dilution IHC~~1:10~50 WB~~1:50~100WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACO2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACO2 Antibody (C-term) - Protein Information | |
| Name ACO2 | |
| Function Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity) | |
| Cellular Location Mitochondrion (By similarity). | |
ACO2 Antibody (C-term) - Related products
AP1936a: ACO2 Antibody (N-term)
AP1936c: ACO2 Antibody (Center)
AP7561b: ACO2 Antibody (C-term)
AP7561c: ACO2 Antibody (Center)
AP7561d: ACO2 Antibody (C-term)
BP1936a: ACO2 Antibody (N-term) Blocking Peptide
BP1936c: ACO2 Antibody (Center) Blocking Peptide
BP7561b: ACO2 Antibody (C-term) Blocking Peptide
ACO2 Antibody (C-term) - Application data
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Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ACO2 antibody (C-term) (Cat.#AP7651b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Western blot analysis of ACO2 (arrow) using rabbit polyclonal ACO2 Antibody (C-term) (Cat.#AP7561b).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACO2 gene (Lane 2) (Origene Technologies).
ACO2 Antibody (C-term) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
REFERENCES
Yu,Z.,Prostate 66 (10), 1061-1069 (2006) Tsui,K.H.,Asian J. Androl. 8 (3), 307-315 (2006) Ahmed,M.,J. Proteome Res. 4 (3), 931-940 (2005)
