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>   home   >   Products   >   Primary Antibodies   >   Tyrosyl tRNA synthetase (YARS) Antibody (N-term)   

Tyrosyl tRNA synthetase (YARS) Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Tyrosyl tRNA synthetase (YARS) Antibody (N-term) AP7580a
    Western blot analysis of anti-YARS Pab (Cat.#AP7580a) in Jurkat cell line lysates (35ug/lane).YARS (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P54577
Other Accession Q4KM49
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 59143 Da
Antigen Region 160-190 aa
Additional Information
Gene ID 8565
Other Names Tyrosine--tRNA ligase, cytoplasmic, Tyrosyl-tRNA synthetase, TyrRS, Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed, YARS
Target/Specificity This Tyrosyl tRNA synthetase (YARS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from the N-terminal region of human Tyrosyl tRNA synthetase (YARS).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTyrosyl tRNA synthetase (YARS) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr).
Cellular Location Cytoplasm.
Citations ( 0 )


Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.


Yang,X.L., Chem. Biol. 14 (12), 1323-1333 (2007)
Jordanova,A., Nat. Genet. 38 (2), 197-202 (2006)
Bonnefond,L., Biochemistry 44 (12), 4805-4816 (2005)

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$ 295.00
$ 99.00
Cat# AP7580a
(40 western blots)
Availability: In Stock
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