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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLIC5 Antibody   

CLIC5 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CLIC5 Antibody AP7583a
    Western blot analysis of anti-CLIC5 Antibody (Cat.#AP7583a) in K562 cell line lysates (35ug/lane). CLIC5(arrow) was detected using the purified Pab.
  • IHC-P - CLIC5 Antibody AP7583a
    Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with CLIC5 antibody (Cat.#AP7583a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZA1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46503 Da
Additional Information
Gene ID 53405
Other Names Chloride intracellular channel protein 5, CLIC5
Target/Specificity This CLIC5 antibody is generated from rabbits immunized with human recombinant CLIC5 protein.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLIC5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLIC5
Function Required for normal hearing (PubMed:24781754). It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture (PubMed:15184393, PubMed:18028448, PubMed:20335315).
Cellular Location Isoform 1: Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Membrane; Single-pass membrane protein. Note=Associates with the cortical actin cytoskeleton. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).
Tissue Location Widely expressed in both fetal and adult human tissues (PubMed:24781754). Isoform 1 is expressed in renal glomeruli endothelial cells and podocytes (at protein level)
Research Areas
Citations (0)

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Chloride intracellular channels are involved in chloride ion transport within various subcellular compartments. CLIC5 specifically associates with the cytoskeleton of placenta microvilli.


Berryman,M., J. Biol. Chem. 279 (33), 34794-34801 (2004)
Suzuki,T.,Epilepsy Res. 50 (3), 265-275 (2002)

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$ 295.00
$ 99.00
Cat# AP7583a
(40 western blots)
Availability: In Stock
Bulk Size
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