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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CABP1 Antibody (C-term)   

CABP1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CABP1 Antibody (C-term) AP7588b
    Western blot analysis of anti-CABP1 Antibody (C-term) (Cat.#AP7588b) in mouse cerebellum tissue lysates (35ug/lane).CABP1(arrow) was detected using the purified Pab.
  • IHC-P - CABP1 Antibody (C-term) AP7588b
    Formalin-fixed and paraffin-embedded human brain tissue reacted with CABP1 antibody (C-term) (Cat.#AP7588b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • WB - CABP1 Antibody (C-term) AP7588b
    CABP1 Antibody (C-term) (Cat. #AP7588b) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CABP1 antibody detected the CABP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZU7
Other Accession O88751, Q9JLK7, Q9N1R0
Reactivity Human, Mouse
Predicted Bovine, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39838 Da
Antigen Region 311-343 aa
Additional Information
Gene ID 9478
Other Names Calcium-binding protein 1, CaBP1, Calbrain, Caldendrin, CABP1
Target/Specificity This CABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-343 amino acids from the C-terminal region of human CABP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCABP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CABP1
Function Modulates calcium-dependent activity of inositol 1,4,5- triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor- induced cellular degeneration (By similarity).
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor; Cytoplasmic side Golgi apparatus. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=L-CaBP1 is associated most likely with the cytoskeletal structures, whereas S-CaBP1 is localized at or near the plasma membrane Isoform S-CaBP1: Cytoplasm, cell cortex. Cell membrane; Lipid-anchor. Note=S- CaBP1 is localized at or near the plasma membrane
Tissue Location Retina and brain. Somatodendritic compartment of neurons. Calbrain was found exclusively in brain where it is abundant in the hippocampus, habenular area in the epithalamus and in the cerebellum
Research Areas
Citations (0)

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CABP1 belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of this protein was only detected in retina and brain. Study of the mouse homolog demonstrated that groups of cells expressing this protein are located in the center or inner border of the inner unclear layer of retina.


Haynes,L.P., Proteomics 6 (6), 1822-1832 (2006) Wingard,J.N., J. Biol. Chem. 280 (45), 37461-37470 (2005) Zhou,H., J. Biol. Chem. 280 (33), 29612-29619 (2005) Haeseleer,F., J. Biol. Chem. 275 (2), 1247-1260 (2000)

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$ 295.00
$ 99.00
Cat# AP7588b
(40 western blots)
Availability: In Stock
Bulk Size
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