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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTPN7 Antibody (S44)   

PTPN7 Antibody (S44)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PTPN7 Antibody (S44) AP7599a
    Western blot analysis of anti-PTPN7 Antibody (S44)(Cat.#AP7599a) in Jurkat cell line lysates (35ug/lane).PTPN7 (arrow) was detected using the purified Pab.
  • IHC-P - PTPN7 Antibody (S44) AP7599a
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PTPN7 Antibody (S44) (Cat.#AP7599a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35236
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40529 Da
Antigen Region 22-51 aa
Additional Information
Gene ID 5778
Other Names Tyrosine-protein phosphatase non-receptor type 7, Hematopoietic protein-tyrosine phosphatase, HEPTP, Protein-tyrosine phosphatase LC-PTP, PTPN7
Target/Specificity This PTPN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from human PTPN7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTPN7 Antibody (S44) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTPN7
Function Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton
Tissue Location Expressed exclusively in thymus and spleen.
Research Areas
Citations (0)

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PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.


Eswaran,J., Biochem. J. 395 (3), 483-491 (2006)
Mustelin,T., J. Mol. Biol. 354 (1), 150-163 (2005)
Pettiford,S.M., Leukemia 17 (2), 366-378 (2003)
Kosaki,K., J. Clin. Endocrinol. Metab. 87 (8), 3529-3533 (2002)

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$ 295.00
$ 99.00
Cat# AP7599a
(40 western blots)
Availability: In Stock
Bulk Size
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