- CITATIONS: 1
|Application ||WB, E|
|Calculated MW||56557 Da|
|Antigen Region||14-43 aa|
|Other Names||Sestrin-1, p53-regulated protein PA26, SESN1, PA26, SEST1|
|Target/Specificity||This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human Sestrin-1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Sestrin-1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth.|
|Tissue Location||Widely expressed.|
Provided below are standard protocols that you may find useful for product applications.
Sestrin-1 is involved in the reduction of peroxiredoxins. This protein may also be regulator of cellular growth.
Budanov,A.V., Science 304 (5670), 596-600 (2004) Peeters,H., Hum. Genet. 112 (5-6), 573-580 (2003) Velasco-Miguel,S., Oncogene 18 (1), 127-137 (1999)
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