|Application ||WB, IHC-P, E|
|Calculated MW||41861 Da|
|Antigen Region||328-357 aa|
|Other Names||Platelet-derived growth factor receptor-like protein, PDGFR-like protein, PDGF receptor beta-like tumor suppressor, PDGFRL, PRLTS|
|Target/Specificity||This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-357 amino acids from the C-terminal region of human PDGFRL.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PDGFRL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in colon, lung and liver.|
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Provided below are standard protocols that you may find useful for product applications.
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
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