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TrkC Antibody

Purified Rabbit Polyclonal Antibody (Pab)

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  • IHC-P - TrkC Antibody AP7688d
    Immunohistochemical analysis of paraffin-embedded H. brain section using TrkC Antibody(Cat#AP7688d). AP7688d was diluted at 1:100 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • WB - TrkC Antibody AP7688d
    TrkC Antibody (Cat. #AP7688d) western blot analysis in U87-MG cell line lysates (35ug/lane).This demonstrates the TrkC antibody detected the TrkC protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16288
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 94428 Da
Additional Information
Gene ID 4916
Other Names NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, NTRK3, TRKC
Target/Specificity This TrkC antibody is generated from rabbits immunized with a his tag recombinant protein of human TrkC.
Dilution IHC-P~~1:100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTrkC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NTRK3
Synonyms TRKC
Function Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain
Research Areas
Citations (0)

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TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.


McGregor, L.M., et al., Genomics 22(2):267-272 (1994).
Shelton, D.L., et al., J. Neurosci. 15 (1 Pt 2), 477-491 (1995).

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$ 295.00
$ 99.00
Cat# AP7688d
(40 western blots)
Availability: In Stock
Bulk Size
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