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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GRK7 Antibody (C-term)   

GRK7 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GRK7 Antibody (C-term) AP7731b
    Western blot analysis of anti-GRK7 Antibody (C-term)(Cat.#AP7731b) in HepG2 cell line lysates (35ug/lane). GRK7(arrow) was detected using the purified Pab.
  • IHC-P - GRK7 Antibody (C-term) AP7731b
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
  • IHC-P - GRK7 Antibody (C-term) AP7731b
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with GRK7 Antibody (C-term) (Cat.#AP7731b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WTQ7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 62212 Da
Antigen Region 508-538 aa
Additional Information
Gene ID 131890
Other Names G protein-coupled receptor kinase 7, G protein-coupled receptor kinase GRK7, GRK7, GPRK7
Target/Specificity This GRK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-538 amino acids from the C-terminal region of human GRK7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGRK7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRK7
Synonyms GPRK7
Function Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
Cellular Location Membrane {ECO:0000250|UniProtKB:Q8WMV0}; Lipid-anchor {ECO:0000250|UniProtKB:Q8WMV0}
Tissue Location Retinal cones, outer and inner segments.
Research Areas
Citations (0)

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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).


Weiss, E.R., et al., J. Neurosci. 21(23):9175-9184 (2001).
Chen, C.K., et al., Mol. Vis. 7, 305-313 (2001).

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$ 295.00
$ 99.00
Cat# AP7731b
(40 western blots)
Availability: In Stock
Bulk Size
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