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NTF3 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NTF3 Antibody (Center) AP7763c
    NTF3 Antibody (Center) (Cat.#AP7763c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NTF3 antibody detected the NTF3 protein (arrow).
    detail
  • IHC-P - NTF3 Antibody (Center) AP7763c
    Formalin-fixed and paraffin-embedded human brain tissue reacted with NTF3 antibody (Center) (Cat.#AP7763c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P20783
Other Accession P18280, Q06AV0, P20181, P25433, Q08DT3
Reactivity Human
Predicted Bovine, Chicken, Mouse, Pig, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 29355 Da
Antigen Region 122-151 aa
Additional Information
Gene ID 4908
Other Names Neurotrophin-3, NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor, NTF3
Target/Specificity This NTF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human NTF3.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNTF3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NTF3
Function Seems to promote the survival of visceral and proprioceptive sensory neurons.
Cellular Location Secreted.
Tissue Location Brain and peripheral tissues.
Research Areas
Citations (0)
citation

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Background

NTF3 is a member of the neurotrophin family that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

References

Hossain,W.A., J. Neurosci. Res. 86 (11), 2376-2391 (2008)
Mercader,J.M., Hum. Mol. Genet. 17 (9), 1234-1244 (2008)
Kalcheim,C.,Proc. Natl. Acad. Sci. U.S.A. 89 (5), 1661-1665 (1992)

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$ 182.50
$ 70.00
Cat# AP7763c
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