CAMKK1 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q8N5S9 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 55735 Da |
Antigen Region | 86-121 aa |
Gene ID | 84254 |
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Other Names | Calcium/calmodulin-dependent protein kinase kinase 1, CaM-KK 1, CaM-kinase kinase 1, CaMKK 1, CaM-kinase IV kinase, Calcium/calmodulin-dependent protein kinase kinase alpha, CaM-KK alpha, CaM-kinase kinase alpha, CaMKK alpha, CAMKK1, CAMKKA |
Target/Specificity | This CAMKK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-121 amino acids from the N-terminal region of human CAMKK1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CAMKK1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CAMKK1 |
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Synonyms | CAMKKA |
Function | Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2- antagonist of cell death. |
Cellular Location | Cytoplasm. Nucleus. |
Provided below are standard protocols that you may find useful for product applications.
Background
CAMKK1 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade.
References
Guest,C.B., PLoS ONE 3 (2), E1606 (2008)
Rudd,M.F., Genome Res. 16 (6), 693-701 (2006)
Ishikawa,Y., FEBS Lett. 550 (1-3), 57-63 (2003)
Matsushita,M., J. Biol. Chem. 274 (15), 10086-10093 (1999)
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