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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   CYP2W1 Antibody (N-term)   

CYP2W1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CYP2W1 Antibody (N-term) AP7792a
    Western blot analysis of lysates from MCF-7, HepG2 cell line (from left to right), using CYP2W1 Antibody (N-term)(Cat. #AP7792a). AP7792a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
  • IHC-P - CYP2W1 Antibody (N-term) AP7792a
    Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP2W1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TAV3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53844 Da
Antigen Region 7-33 aa
Additional Information
Gene ID 54905
Other Names Cytochrome P450 2W1, 11414-, CYPIIW1, CYP2W1
Target/Specificity This CYP2W1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-33 amino acids from the N-terminal region of human CYP2W1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCYP2W1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP2W1
Function Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Actives also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743).
Cellular Location Endoplasmic reticulum lumen. Cell membrane. Note=About 8% are expressed on the cell surface.
Tissue Location Very low levels are detected in fetal and adult tissues. Highly expressed in several tumor samples, in particular colon and adrenal tumors
Research Areas
Citations (0)

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CYP2W1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.


Gomez,A., Pharmacogenomics 8 (10), 1315-1325 (2007)
Karlgren,M., Biochem. Biophys. Res. Commun. 341 (2), 451-458 (2006)
Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)

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$ 295.00
$ 99.00
Cat# AP7792a
(40 western blots)
Availability: In Stock
Bulk Size
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