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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DSG2 Antibody (N-term T160)   

DSG2 Antibody (N-term T160)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DSG2 Antibody (N-term T160) AP7795a
    Western blot analysis of anti-DSG2 Antibody (N-term T160) (AP7795a) in T47D cell line lysates (35ug/lane). DSG2 (arrow) was detected using the purified Pab.
  • FC - DSG2 Antibody (N-term T160) AP7795a
    Flow cytometric analysis of MCF-7 cells using DSG2 Antibody (N-term T160) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14126
Other Accession NP_001934
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 122294 Da
Antigen Region 145-216 aa
Additional Information
Gene ID 1829
Other Names Desmoglein-2, Cadherin family member 5, HDGC, DSG2, CDHF5
Target/Specificity This DSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-216 amino acids from the N-terminal region of human DSG2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDSG2 Antibody (N-term T160) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DSG2
Synonyms CDHF5
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Cellular Location Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
Tissue Location All of the tissues tested and carcinomas.
Research Areas
Citations (0)

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Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This protein is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in the DSG2 gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.


Posch,M.G., Mol. Genet. Metab. 95 (1-2), 74-80 (2008)
Yu,C.C., J. Formos. Med. Assoc. 107 (7), 548-558 (2008)

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Cat# AP7795a
(40 western blots)
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