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TESK2 Antibody (Center C225)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TESK2 Antibody (Center C225) AP7821f
    Anti-TESK2 Antibody (Center) at 1:500 dilution + HL-60 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - TESK2 Antibody (Center C225) AP7821f
    Formalin-fixed and paraffin-embedded human testis tissue reacted with TESK2 antibody (Center)(Cat.#AP7812f), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96S53
Other Accession Q924U5, Q8VCT9
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 63639 Da
Antigen Region 210-240 aa
Additional Information
Gene ID 10420
Other Names Dual specificity testis-specific protein kinase 2, Testicular protein kinase 2, TESK2
Target/Specificity This TESK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human TESK2.
Dilution WB~~1:500
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTESK2 Antibody (Center C225) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TESK2
Function Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis.
Cellular Location Nucleus.
Tissue Location Predominantly expressed in testis and prostate. Found predominantly in non-germinal Sertoli cells
Research Areas
Citations (0)

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TESK2 is a dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. TESK2 phosphorylates cofilin at Ser-3. It may play an important role in spermatogenesis. This nuclear enzyme is thought to be activated by autophosphorylation on Ser-219. Expression is predominantly in testis and prostate, with highest concentrations in nongerminal Sertoli cells.


Toshima,J.,J. Biol. Chem. 276 (33), 31449-31458 (2001)
Rosok,O., Genomics 61 (1), 44-54 (1999)

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$ 295.00
$ 99.00
Cat# AP7821f
(40 western blots)
Availability: In Stock
Bulk Size
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