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TRAF2 AntibodyPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP7825d | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP7825d-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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TRAF2 Antibody - Product info | |
| Application | WB
|
| Primary Accession | Q12933 |
| Other Accession | NP_066961.2 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 55859 Da |
TRAF2 Antibody - Additional info | |
| Gene ID 7186 | |
| Other Names TRAF2; TRAP3; TNF receptor-associated factor 2; E3 ubiquitin-protein ligase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3 | |
| Target/Specificity This TRAF2 Antibody is generated from rabbits immunized with recombinant protein of human TRAF2. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions TRAF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
TRAF2 Antibody - Protein Information | |
| Name TRAF2 | |
| Synonyms TRAP3 | |
| Function Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis Required for normal antibody isotype switching from IgM to IgG Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'- linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin- protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain | |
| Cellular Location Cytoplasm. | |
TRAF2 Antibody - Related products
AM1895a: TRAF2 antibody ( Ascites)
AP7825b: TRAF2 Antibody (C-term)
AP7825c: TRAF2 Antibody (Center)
RI15437: TRAF2 predesign siRNA
DC06383: Human TRAF2 cDNA Clone
LY11558a: TRAF2 Over-expression Lysate
BP7825b: TRAF2 Antibody (C-term) Blocking Peptide
TRAF2 Antibody - Application data
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TRAF2 Antibody (Cat. #AP7825d) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TRAF2 antibody detected the TRAF2 protein (arrow).
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TRAF2 Antibody (Cat. #AP7825d) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the TRAF2 antibody detected the TRAF2 protein (arrow).
TRAF2 Antibody - Research Areas
AntibodiesBiological ProcessCellular ProcessPositive Regulation Of Biological ProcessPositive Regulation Of Cellular ProcessRegulation Of Cell DeathRegulation Of Programmed Cell DeathRegulation Of ApoptosisRegulation Of PhosphorylationRegulation Of Phosphate Metabolic ProcessRegulation Of Phosphorus Metabolic ProcessIntracellular Signaling CascadeProtein Kinase CascadeRegulation Of Kinase ActivityRegulation Of Protein Kinase ActivityRegulation Of Transferase ActivityRegulation Of Molecular FunctionPositive Regulation Of Molecular FunctionPositive Regulation Of Cell DeathPositive Regulation Of ApoptosisPositive Regulation Of Programmed Cell DeathRegulation Of Catalytic ActivityRegulation Of Cell CommunicationRegulation Of Response To StimulusPositive Regulation Of Catalytic ActivityPositive Regulation Of Kinase ActivityPositive Regulation Of Protein Kinase ActivityRegulation Of Multicellular Organismal ProcessRegulation Of Signal Transduction
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