|Application ||WB, IHC-P, E|
|Other Accession||Q6P799, P26638, Q4R4U9, P26636, Q9GMB8|
|Predicted||Bovine, Hamster, Monkey, Mouse, Rat|
|Calculated MW||58777 Da|
|Antigen Region||394-422 aa|
|Other Names||Serine--tRNA ligase, cytoplasmic, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase, SARS, SERS|
|Target/Specificity||This SARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-422 amino acids from the C-terminal region of human SARS.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SARS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|
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Provided below are standard protocols that you may find useful for product applications.
Seryl-tRNA synthetase belongs to the class II amino-acyl tRNA family. This enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts.
Shimada,N., J. Biol. Chem. 276 (50), 46770-46778 (2001)
Shah,Z.H., Hum. Mutat. 17 (5), 433-434 (2001)
Heckl,M., FEBS Lett. 427 (3), 315-319 (1998)
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