YARS2 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q9Y2Z4 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 53199 Da |
Antigen Region | 43-71 aa |
Gene ID | 51067 |
---|---|
Other Names | Tyrosine--tRNA ligase, mitochondrial, Tyrosyl-tRNA synthetase, TyrRS, YARS2 |
Target/Specificity | This YARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of human YARS2. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | YARS2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | YARS2 |
---|---|
Function | Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). |
Cellular Location | Mitochondrion matrix |
Provided below are standard protocols that you may find useful for product applications.
Background
YARS2 catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)
References
Bonnefond,L., Structure 15 (11), 1505-1516 (2007)
Bonnefond,L., RNA 11 (5), 558-562 (2005)
Bonnefond,L., Biochemistry 44 (12), 4805-4816 (2005)
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