- CITATIONS: 1
|Application ||WB, IHC-P, E|
|Other Accession||Q5I0L3, Q8BYL4|
|Calculated MW||53199 Da|
|Antigen Region||399-427 aa|
|Other Names||Tyrosine--tRNA ligase, mitochondrial, Tyrosyl-tRNA synthetase, TyrRS, YARS2|
|Target/Specificity||This YARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the C-terminal region of human YARS2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||YARS2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr).|
|Cellular Location||Mitochondrion matrix|
Provided below are standard protocols that you may find useful for product applications.
YARS2 catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
Bonnefond,L., Structure 15 (11), 1505-1516 (2007)
Bonnefond,L., RNA 11 (5), 558-562 (2005)
Bonnefond,L., Biochemistry 44 (12), 4805-4816 (2005)
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