|Application ||WB, IHC-P, E|
|Calculated MW||140476 Da|
|Antigen Region||251-279 aa|
|Other Names||Valine--tRNA ligase, Protein G7a, Valyl-tRNA synthetase, ValRS, VARS, G7A, VARS2|
|Target/Specificity||This VARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-279 amino acids from the N-terminal region of human VARS.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VARS Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. This protein belongs to the class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.
Jiang,S., FEBS Lett. 579 (27), 6049-6054 (2005)
Bonnefond,L., Biochemistry 44 (12), 4805-4816 (2005)
Xie,T., Genome Res. 13 (12), 2621-2636 (2003)
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