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FKBP1B Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FKBP1B Antibody (N-term) AP7868d
    Western blot analysis of FKBP1B antibody (N-term) (Cat.# AP7868d) in 293 cell line lysates (35ug/lane). FKBP1B (arrow) was detected using the purified Pab.
  • WB - FKBP1B Antibody (N-term) AP7868d
    Western blot analysis of FKBP1B antibody (N-term) (Cat.# AP7868d) in mouse cerebellum tissue lysates (35ug/lane). FKBP1B (arrow) was detected using the purified Pab.
  • IHC-P - FKBP1B Antibody (N-term) AP7868d
    FKBP1B Antibody (N-term) (Cat.# AP7868d) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP1B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - FKBP1B Antibody (N-term) AP7868d
    Confocal immunofluorescent analysis of FKBP1B Antibody (N-term)(Cat#AP7868d) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P68106
Other Accession P97534, Q8HYX6, Q9Z2I2, P68107
Reactivity Human, Mouse
Predicted Bovine, Rabbit, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 11783 Da
Antigen Region 16-46 aa
Additional Information
Gene ID 2281
Other Names Peptidyl-prolyl cis-trans isomerase FKBP1B, PPIase FKBP1B, 126 kDa FK506-binding protein, 126 kDa FKBP, FKBP-126, FK506-binding protein 1B, FKBP-1B, Immunophilin FKBP126, Rotamase, h-FKBP-12, FKBP1B, FKBP126, FKBP1L, FKBP9, OTK4
Target/Specificity This FKBP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human FKBP1B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFKBP1B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FKBP12.6, FKBP1L, FKBP9, OTK4
Function Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Cellular Location Cytoplasm. Sarcoplasmic reticulum
Tissue Location Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.
Research Areas
Citations (0)

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FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.


Arakawa H., Nagase H.Biochem. Biophys. Res. Commun. 200:836-843(1994)
Lam E., Martin M.M., Timerman A.P.Biol. Chem. 270:26511-26522(1995)
Deivanayagam C.C., Carson M.Acta Crystallogr. D 56:266-271(2000)

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$ 295.00
$ 99.00
Cat# AP7868d
(40 western blots)
Availability: In Stock
Bulk Size
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