|Application ||WB, E|
|Calculated MW||59086 Da|
|Antigen Region||89-118 aa|
|Other Names||Cytochrome P450 4Z1, CYPIVZ1, CYP4Z1|
|Target/Specificity||This CYP4Z1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human CYP4Z1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CYP4Z1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein|
|Tissue Location||Preferentially detected in breast carcinoma tissue and mammary gland, whereas only marginal expression is found in all other tested tissues.|
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Provided below are standard protocols that you may find useful for product applications.
CYP4Z1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
Savas,U., Arch. Biochem. Biophys. 436 (2), 377-385 (2005)
Rieger,M.A., Cancer Res. 64 (7), 2357-2364 (2004)
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